* Latest "Gene-Amplification" in the News *
CRISPR controls obesity in mice by amplifying rather than editing genes FierceBiotech
The genes SIM1 and MC4R regulate food intake by signaling the feeling of being full, and mutations in even just one copy of either gene can lead to obesity.
Androgen Receptor Gene Amplification: A Possible Molecular Mechanism for Androgen Deprivation Therapy Failure in Prostate Cancer. UroToday
amplification of the androgen receptor (AR) gene may cause failure of androgen deprivation therapy in prostate cancer,
New Products Posted to GenomeWeb: Cellecta, Indigo, Expedeon, More GenomeWeb
Cellecta DriverMap RNA-Seq Panels, Analysis Software. Cellecta has launched five DriverMap Predesigned RNA-Seq panels, including the Human Cell Marker ...
Seno Medical Instruments touts Imagio breast cancer subtype ID trial results Mass Device
Seno Medical Instruments today released results from a study of its Imagio opto-acoustc imaging system intended to diagnose breast cancer, touting that both ...
Response Rates in Treatment of MET-Amplified NSCLC OncLive
Anne S. Tsao, MD, considers the use of crizotinib (Xalkori) for patients with MET amplification, after progression on chemotherapy in non–small cell lung ...
The Federal Circuit Still Doesn't Get Diagnostic Claims - Intellectual Property - United States Mondaq News Alerts
In Roche Diagnostics the Federal Circuit continued its failure to recognize that diagnostic claims were not patent ineligible because they used a natural law.
A male-expressed rice embryogenic trigger redirected for asexual propagation through seeds Nature.com
The molecular pathways that trigger the initiation of embryogenesis after fertilization in flowering plants, and prevent its occurrence without fertilization, are not ...
Biomarker-Based Phase II Trial of Savolitinib in Patients with Advanced Papillary Renal Cell Cancer UroToday
safety and efficacy of savolitinib in patients with papillary renal cell carcinoma (PRCC) according to MET status, single-arm, multicenter phase II study of ...
Faster, cheaper test can help predict risk of metastasis in prostate cancer patients Medical Xpress
For men newly diagnosed with prostate cancer or patients previously treated, the risk of metastasis is a crucial determinant of whether to choose conservative ...
BeiGene bags Asian rights to Zymeworks' HER2 bispecifics FierceBiotech
BeiGene has paid Zymeworks $40 million for the Asian rights to HER2-targeted bispecific antibodies ZW25 and ZW49. The agreement gives Zymeworks upfront ...
I1307K and E1317Q polymorphism in the APC gene in colorectal cancer patients and two groups in Colombian population. Science 2.0
Ana María Mora1, Andrés Gutiérrez2, Marina Ordóñez1, Amparo Mora3, Antonio Ormaza3-4, Germán Junca3-4, Alejandro Giraldo2-3 1 Universidad de los ...
'Of course it's not ethical': shock at gene-edited baby claims The Guardian
Chinese geneticist He Jiankui's claim to have altered embryos prompts outcry from scientists.
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Gene amplification - Wikipedia
Gene amplification refers to a number of natural and artificial processes by which the number of copies of a gene is increased "without a proportional increase in other genes". Artificial DNA amplification for research or diagnosis can be conducted through methods including:
Definition of gene amplification - NCI Dictionary of ...
Gene amplification is common in cancer cells, and some amplified genes may cause cancer cells to grow or become resistant to anticancer drugs. Genes may also be amplified in the laboratory for research purposes.
Gene amplification | definition of gene amplification by ...
gene amplification a process by which the number of copies of a gene is increased in certain cells because extra copies of DNA are made in response to certain signals of cell development or of stress from the environment. In humans this process is seen most often in malignant cells.
Gene amplification - Biology-Online Dictionary | Biology ...
Gene amplification is the process of duplicating a specific gene. This amplification increases the frequency of the gene inside the cell . Consequently, it also leads to the amplification of the phenotype (e.g. the proteins ) that the gene confers (or code for).
Gene amplification - definition of gene amplification by ...
Gene amplification is the production of many copies of genes located on a restricted region of the chromosome and it is common in cancer cells.
Gene amplification in cancer.
Gene amplification in cancer. Albertson DG(1). Author information: (1)Cancer Research Institute and Comprehensive Cancer Center, University of California-San Francisco, San Francisco, CA 94143, USA. email@example.com Gene amplification is a copy number increase of a restricted region of a chromosome arm.
Gene amplification | Define Gene amplification at ...
gene amplification in Science gene amplification An increase in the number of copies of a gene in a cell, resulting in an elevation in the level of the RNA or protein encoded for by the gene and a corresponding amplification of the phenotype that the gene confers on the cell.
GENE AMPLIFICATION | definition in the Cambridge English ...
Somatic recombination, gene amplification and cancer. From Cambridge English Corpus Overexpression can happen in one of three ways: as a result of gene amplification , impaired protein degradation, or chromosomal translocation.
Gene Amplification - an overview | ScienceDirect Topics
Gene amplification usually results in enhanced expression of the amplified gene and amplification of some proto-oncogenes is an important mechanism in the progression of some types of tumors. It is unclear why amplification characteristically develops in some types of tumors and not in others.
National Human Genome Research Institute (NHGRI)
Gene amplification is an increase in the number of copies of a gene sequence. Cancer cells sometimes produce multiple copies of genes in response to signals from other cells or their environment. The term also can refer to polymerase chain reaction (PCR), a laboratory technique that is used by scientists to amplify gene sequences in a test tube.